If you are a Medicare Fee-for-Service patient, you can receive same-day ZILRETTA approval. Talk to your doctor today.
It’s time you said, “Enough!”
Suffering doesn’t build character—it just hurts. There is no reward for waiting until it becomes unbearable. But there is a treatment that may help: ZILRETTA—a single injection that can provide major knee pain relief for 3 months.
Give your knee
the Z
ZILRETTA is the first and only FDA-approved treatment for osteoarthritis knee pain that uses extended-release microsphere technology, studied in multiple clinical trials on hundreds of patients.
So, stop tolerating knee pain. Give your knee the Z. Not next month. Not next year. Talk to a doctor now.
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What’s so special about ZILRETTA?
It’s the microspheres
They’re tiny particles that are so small, they cannot be seen by the naked eye. Once injected into the knee, the microspheres stay put, slowly and continually releasing medicine for about 3 months.
It’s the staying power
ZILRETTA microspheres stay right in your knee joint—right where the pain is. After releasing all their medicine into the knee joint, the microspheres break down and turn into carbon dioxide and water, which are naturally found in the body.
What’s so special about ZILRETTA?
See how ZILRETTA microsphere technology works
Is it safe?
In clinical studies, ZILRETTA was shown to be generally safe
The most common side effects of ZILRETTA were similar to those seen in people who received a saltwater injection:
- Joint pain
- Joint Swelling
- Sore throat and runny nose
- Bruising
- Headache
- Back pain
- Upper respiratory tract infection
These are not all of the possible side effects of ZILRETTA. Please see Important Risk Information and the full Prescribing Information. Always contact your doctor if you have questions or experience any side effects.
News for people with
Type 2 diabetes
In a small clinical trial of people with controlled Type 2 diabetes, minimal elevation in their blood glucose level was experienced after treatment with ZILRETTA vs another corticosteroid.
Note: Corticosteroids may increase blood glucose levels. Individual patient experience may differ from what was seen in this study. The clinical significance of this information is unknown.
Results matter
ZILRETTA may provide the relief you’ve been hoping for
In the main clinical study, a single injection of ZILRETTA reduced knee pain for 3 months. What’s more, many people treated with
ZILRETTA experienced pain relief beyond month 3, through month 4.
~70% of study participants had no
to mild knee pain at 3 months
Some patients in this study did not experience a 3-month duration of pain relief.
See what people like you are saying about ZILRETTA
Our Patient Experience Program gathered feedback from patients as they managed their OA knee pain with ZILRETTA. 306 patients
with osteoarthritis knee pain, invited to enroll in this survey by their doctors who decided to prescribe them ZILRETTA, reported these
results 3 months after their ZILRETTA injection:
93% of patients reported
experiencing satisfactory
relief from OA after receiving
an injection of ZILRETTA
88% of patients indicated that
they would recommend
ZILRETTA for others with
OA knee pain
Individual results may vary. Talk with your doctor about all treatment options.
Hear more from actual ZILRETTA patients
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Indication and Important Risk Information
What is ZILRETTA?
ZILRETTA® (triamcinolone acetonide extended-release injectable suspension) is an extended-release corticosteroid approved to manage osteoarthritis knee pain. The benefits and risks of repeat injections have not been demonstrated.
Who should not receive ZILRETTA?
You should not receive a ZILRETTA injection if you are allergic to corticosteroids, triamcinolone acetonide, or any other component of the product.
What possible side effects of corticosteroids could occur with ZILRETTA?
- Rare serious allergic reactions
- Effects in the injected knee such as infection (with pain, swelling and restricted motion) or joint damage
- Increased chance of getting an infection, and a decreased ability to fight an infection
- Effects on hormone production. These effects can be reversible
- Elevated blood pressure, sodium and water retention, and potassium loss
- Intestinal perforation if you have certain gastrointestinal disorders
- Weakening of bones
- Changes in behavior or mood disturbances
- Increased pressure inside the eye
What are the most common side effects of receiving a ZILRETTA injection?
In multiple clinical trials, the most common side effects seen in people taking ZILRETTA were joint pain, headache, joint swelling, back pain, sore throat and runny nose, upper respiratory tract infection, and bruising.
What should you tell your doctor BEFORE receiving a ZILRETTA injection?
Tell your doctor about all of the medications you are taking (including both prescription and over-the-counter medicines) and about any medical conditions, especially if you have high blood pressure, heart disease, ulcers, diverticulitis or other gastrointestinal disorders, kidney problems, diabetes, glaucoma, behavior or mood disorders, and/or infections.
What should you tell your doctor AFTER receiving a ZILRETTA injection?
Contact your doctor if you develop a fever or other signs of infection, have an increase in pain along with swelling of the injected knee, restriction of joint motion, or a general feeling of discomfort. Contact your doctor immediately if you are exposed to chicken pox or measles, or for any new or worsening changes in behavior or mood.
These are not all of the possible side effects with ZILRETTA or corticosteroid medications. Please see the full Prescribing Information at www.ZILRETTALabel.com/PI.pdf. Always contact your doctor if you have questions or experience any side effects.
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.
The Z Team is here to help
Ready to get started on your treatment with ZILRETTA?
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844-353-9466
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